Showing posts with label Herd Immunity. Show all posts
Showing posts with label Herd Immunity. Show all posts

Thursday, March 10, 2011

ThinkTwice and Polio: An Idiot's Guide to Critical Thinking

As he seems to do several times a week, Mr. Hubbs attempted to leave a comment on one of the blog posts here with a lot of nonsense mixed in with links to numerous anti-vaccine websites (including his own personal website several times).  One of his latest comments included the following quote:
"See if you can do your next blog page as to an analysis on this document? There sure are allot of references in it! But I won't add confusion to your personal issues and use the word "fully" again, you can just judge for yourself. Do a comparison against your figures? Like I said, the information is and has been all controlled. The polio vaccine: a critical assessment of its arcane history, efficacy, and long-term health-related consequence.  http://www.thinktwice.com/Polio.pdf"  ~Lowell Hubbs
This is yet another example of how Mr. Hubbs doesn't understand the difference between peer-reviewed science and an editorial.  Thus, I'll try to walk him through the process one more time although I'm fairly certain he won't be swayed since antivaxers rarely, if ever, rely upon logic or fact when they argue their points.

First of all notice that the article Mr. Hubbs cites here is hosted on the thinktwice website.  So the first thing we need to know is what that particular website is associated with.  Mr. Hubbs may feel this isn't important, but the point is you wouldn't want to read a "study" or "article" that claims smoking is actually healthy and that it doesn't cause cancer as has been proven in the past only to find that article was written by tobacco researchers who work for Altria nor would you give it credibility when you found it was hosted on the Altria website.

For that reason I examined the thinktwice website and tried to determine who was associated with it.  Unfortunately the "about us" page doesn't list any names or any doctors who are affiliated with the website, so I have no way to know who runs or manages the website nor do I know their qualifications.  They do however list a nice disclaimer that includes such phrases as:
  • "Some of the information presented on the Thinktwice Global Vaccine Institute website may conflict with data presented elsewhere. Therefore, readers are encouraged to remain circumspect and use discretion when interpreting contradictory, complex or confusing concepts."
  • "Vaccine recommendations change rapidly. Immunization schedules are periodically revised. Therefore, the FDA and CDC -- not the Thinktwice Global Vaccine Institute -- should be consulted for the most up-to-date information regarding who should or should not receive vaccines, at what ages, and the number of doses."
  • "For official information about vaccines, contact vaccine manufacturers, the FDA, CDC or World Health Organization"
  • "The Thinktwice Global Vaccine Institute does not recommend for or against vaccines. Parents and other concerned people must make this decision on their own. Because the data on this website tends to implicate vaccines (find fault with them), readers are advised to balance the data presented here with data presented by "official" sources of vaccine information, including pharmaceutical companies, the FDA, CDC and World Health Organization."
So aside from the fact that it is glaringly obvious Mr. Hubbs has failed to read the disclaimer, it seems apparent that those behind thinktwice are at least being honest about the fact that they have no credentials and shouldn't be trusted to offer objective advice.  Yet Mr. Hubbs still believes this is a trusted unbiased source worthy of citing?  When will the man learn.
 
So since we can't determine who is behind the website, what else do they have to offer?  Well as is the case with every single antivaxer website I have found thus far, they have an online store which can sell you books and various supplements.  In this  case they are pitching a colon cleansing product called "Herbal Fiberblend" for only $40, or a product called "HumiKleanse" for Heavy Metal Chelation for only $25.  Don't ask for any science to prove either of these products actually work however, because there isn't any.  They are marketed as nutritional supplements and therefore are not required to prove they do anything other than drain your wallet.

Looking further on the website, there are also the obligatory "homeopathy kits" ranging in price from $29.95 all the way up to $99, as well as random pamphlets and books an even PowerPoint presentations ranging from $49 to $99... but hey at least the $99 presentation includes a whopping 32 slides about vaccinations, so that must be a bargain.
 
Let me stop right here and ask if you went to the CDC or FDA website and they had a store where they would sell you books and pro-vaccine pamphlets and slideshows... would you believe for a second that those websites were as reputable and other websites which offer their information for free in an effort to simply educate the public?  If you visited the website of a major pharmaceutical manufacturer and they were selling books for $19.95 that show how their pills can solve all of your ailments and that there are no known side effects... would you actually believe that book is in any way unbiased?  Could you trust the information shown to you was impartial and fair if you knew their goal was to have you pack your online shopping cart with various remedies and books and emergency supplies?  No you wouldn't - because real unbiased science doesn't rely upon pushing the reader towards an online store.  Real science and real unbiased information is only interested in sharing that information, which is why you will never see a reputable website or medical journal offer to sell you some random supplement as a promotional tie-in to the information being disseminated.

So we have clearly established this website is an antivaxer joke with a sole purpose of selling goods to ignorant masses who don't understand science.  Now it is time to move on to the real purpose of this post and that is to review the article Mr. Hubbs feels is so worthy to be cited time and time again.

The first thing you notice about this article is that it is not a research study nor is it peer-reviewed.  That should be red flag number one that you aren't getting the whole picture.  Red flag number two is that there is only one author listed and that author (Neil Miller) is not a doctor, research scientist, or medical researcher.  In fact Mr. Miller's education was an undergrad degree in Psychology and as far as we can tell he has never participated in or added his name to any peer-reviewed science published in a reputable medical journal.

Red flag number three is that this article is "published" not in a true reputable and/or respected medical journal, but rather in Medical Veritas which as we have discussed in the past is not a real medical journal but rather a journal created by the anti-vaccine and anti-mainstream medicine community so they could pack it full of their unsupported and non peer-reviewed opinion pieces and then claim those pieces were "published".

As you actually begin reading the article that Mr. Miller has drafted, you soon realize that he makes numerous accusations but with very little supporting evidence, and the evidence he does use is manipulated to make suggestions or correlations which are unproved.  Case in point, Mr. Miller claims that "Polio cases skyrocketed after diphtheria and pertussis vaccines were introduced" and he shows a chart which lists the number of cases of polio and how from a period in the 1930s to a period in the 1950s the number of cases seemed to be rising exponentially. 

As any good antivaxer would do, Mr. Miller automatically picks a vaccine to arbitrarily blame for this rise, and he doesn't bother to consider any other alternatives.  Unfortunately for Mr. Miller, polio was already on the rise long before the diphtheria and pertussis vaccines were introduced and continued to rise after their introduction even in the portion of the population which wasn't receiving normal vaccinations.  Also, even though vaccinations for diphtheria and pertussis continued to be given throughout the next several decades (and are still given today) polio has not increased as a result.  Miller is guilty of the assumption that correlation equals causation, and either out of ignorance or intellectual dishonesty he fails to recognize or report the glaring holes in his theory.

Miller then goes on to postulate that polio is caused by an "excessive use of sugars and starches" and he uses quotes from the 1940s that suggested nations that used the most amount of sugar also had the highest rates of polio.  He also suggests polio outbreaks were always more severe in the summer months and that was due to children drinking soft drinks, eating ice cream, or ingesting other products which are artificially sweetened.  Mr. Hubbs and other antivaxers have made these claims in the past and as always they are proven to be entirely without merit.

Notice that Miller drills down on one particular state (North Carolina) and shows how their rates of polio dropped after they were warned to decrease the amount of sugar intake.  However Miller offers no data on surrounding states to determine if these numbers were witnessed elsewhere, nor does he provide any evidence beyond personal opinion that sugar intake in North Carolina actually decreased.  He does mention that one ice cream manufacturer shipped one million pounds less in a single week after the sugar-causes-polio claim was first reported, but Miller fails to mention the reason for that drop in shipments nor does he provide any evidence beyond that one week.

The problem is, this was the 1940s and it wasn't like companies had automated shipping lines or replenishment on demand ordering systems.  Besides the fact it wouldn't be feasible for a manufacturer to even be notified that they shouldn't ship massive amounts of ice cream during a single week, there is no background data to support the theory that sugar consumption in general actually decreased.  For all we know this one particular manufacturer (which Miller conveniently fails to mention by name) could have had a plant malfunction or a union strike, or a problem obtaining milk supplies or any other issue which was the root cause for them being unable to produce the same amount of ice cream.

It is quite possible that other manufacturers shipped even more ice cream to North Carolina during this same period, but we aren't given that data.  We are only given the select pieces of data that Miller wishes us to read in order for him to make his scientifically unsupported position.  A true study would not have relied upon such assumption and rather would have examined numerous states, their rates of polio, the amount of sugar consumed per capita from all known sources, and any other underlying factors which could have been to blame for a reduction in the number of cases (such as a unusually wet or humid summer resulting in less human to human contact, improved sanitation resulting in less fecal-oral contamination, more awareness of the disease resulting in less human transmission, or countless other factors).

A true study would have at least examined other potential causes or other factors, but Miller isn't concerned with digging deep, he is only concerned with cherry-picking numbers and statements to support his anti-vaccine viewpoint.  Case in point out of the 50 US states, Miller selects five states that reported more cases of polio after the development and usage of the polio vaccine than they did previously.  Although he cannot directly connect the rise in polio to the vaccine (as he cites no supporting studies which show those that were vaccinated were the same people diagnosed with polio) he does attempt to make a correlation between the two.  I would have loved to examine the figures for the 45 remaining states to determine if they too saw an increase in the number of polio cases after the vaccine was used, but unfortunately Miller doesn't tell us where he obtained his numbers... merely that they were sourced from "U.S. Government statistics".

Does it strike Miller as odd that the five states he has represented (Vermont, Rhode Island, New Hampshire, Connecticut , and Massachusetts) are all in New England and all border one another?  Does it strike Miller as strange that although the vaccine was in widespread use nationwide that he was unable to find any other areas that saw this sudden spike in the number of cases of polio?  Did Miller consider other possibilities for these increases such as an outbreak in New England?  Obviously not.  This is why such an article would never be taken seriously in a true medical journal and why Miller had to resort to publishing this idiocy in Medical Veritas and on his own website.

The fact is, across the entire US there were close to 58,000 cases of polio in 1952, whereas after a massive vaccination campaign we witnessed a massive decrease in cases to around 15,000 in 1956, to just over 3000 in 1960, and in 1965 there only 72.  A few years after that in 1969 there were less than 20 total across the entire US, and by by mid 70s there were only around 8 cases per year.  Does Miller believe this is all due to the US vastly decreasing the amount of sugar intake? 

If that is Miller's suggestion, then he is being incredibly dishonest because sugar consumption in the US has actually increased during that same period from 6,846,000 tons in 1948 to 9,884,000 tons in 1969.  Unlike Miller I would like to disclose that those figures are total across the US and are not broken down per capita nor did I cherry pick just a few select states to make a point.  However it should be noted that per capita sugar consumption rose during this same period.  I know this because I am capable of doing basic math, and according to the US Census Bureau the US population was 146,631,302 in 1948 and 202,676,946 in 1969.  That tells us that American consumption of sugar in 1948 was 93.4lbs of sugar per person, while it was 97.5lbs of sugar per person in 1969.

Note to Mr. Hubbs:  There are 2,000lbs of sugar in a ton, thus 6,846,000 tons of sugar equates to 13,692,000,000 pounds.  If you divide that figure by the total population of 146,631,302 your end result is 93.37706079, or roughly 93.4 pounds of sugar per capita.  Math doesn't lie.

In fact actual consumption per capita continued to rise until the development of High Fructose Corn Syrup (HFCS) which started to supplant sugar in many of the foods and drinks Americans consume beginning in the 1970s.  With all of this being said, one might think if Miller's hypothesis is correct we would have seen a massive increase in the cases of polio as sugar consumption rose, but sadly for Miller that wasn't the case and in fact the opposite was true.  That isn't to say more sugar consumption is good for people by any means, but it obviously doesn't relate to the number of nationwide cases of polio either.

Miller then goes on to suggest the vaccine isn't actually helpful and rather it is responsible for causing polio.  He also suggests polio was on a decline on its own before the vaccine was introduced, but there is some clever word play used here.  Miller's actual quote is "from 1923 to 1953, before the Salk killed-virus vaccine was introduced, the polio death rate in the United States and England had already declined on its own". 

Notice the clever diversionary terms "death rate".  Miller isn't saying the cases of polio decreased which is what so many antivaxers don't understand.  The numbers I have shown earlier clearly show the number of cases of polio was still increasing at a rapid pace until after mass vaccination programs took effect.  Miller attempts to confuse people by focusing on the death rate as if that is significant, but once again he is cherry picking figures to support his viewpoint.  Notice that at no time does Miller suggest actual cases of polio were on the decrease before the vaccine, merely that the death rate was on the decrease.  This begs the question on why Miller would think polio by itself was perfectly fine provided it doesn't kill people.  I'm sure all of the paralyzed polio victims who have suffered for decades due to this disease would be happy to hear that Mr. Miller doesn't feel their disease is all that significant since it didn't kill them.

Back to reality, the reason that fewer people (as a percentage of polio cases) were actually dying from polio from the 1920s to the 1950s was not because polio had magically transformed from a deadly disease to merely a harmful disease.  Instead, the decrease in deaths was due in no small part to advancements in treatment of polio such as massage for muscle relaxation, confining patients to bed, increased usage of iron lungs, and perhaps most importantly usage of antibiotics to prevent infections.

As you can see, a little objective analysis of Miller's work easily shows gaping flaws in logic, blatant intellectual dishonestly, misleading conclusions, and even factual errors.  I could easily spend several days identifying the countless significant errors throughout the entire article, but at the end of the day no amount of facts or figures is about to sway a devoted antivaxer.  In their minds Miller is a hero for trying to suggest a vaccine causes more harm that good no matter how much evidence exists to the contrary.

Obviously antivaxers like Mr. Hubbs aren't intelligent enough to examine such a document and identify the gaping flaws and therefore they just accept it at face value.  The most comical aspect of this is the fact that Miller actually makes a reference to the concept of herd immunity (second page of the document under item 5) which is the total inverse of what Mr. Hubbs believes, but it is pretty clear that Mr. Hubbs never actually bothers to read the sources he cites and instead is lucky to make it beyond the title and the abstract.

Is it any wonder why nobody will ever take the antivaxer movement seriously?  I think not.

Wednesday, February 23, 2011

Vaccine Philosophical Exemptions: An Anti-Vaxer Guide of Nonsense

If you have been keeping up with some of Lowell Hubbs' comments on previous blog posts about Herd Immunity, you may have seen the following comment he recently added:
"This is the best in condensed form written arguement against vaccines I have ever read. Vaccine philosophical exemptions: A moral and ethical imperative. This document as well shows you clear proof as to why there is NO real science behind the term "herd immunity". Herd Immunity is a MYTH! Go ahead and provide some refute to the article, and again regardless of if you admit it, it is fully referenced."  ~Lowell Hubbs 
Mr. Hubbs then went on to list the following article:  Vaccine philosophical exemptions: A moral and ethical imperative, published Friday, February 18, 2011 by Alan Phillips.  The full text can be found here.

With that said, let's look at the idiotic editorial that Mr. Hubbs has provided (because contrary to what Mr. Hubbs may think, this is in no way a research study nor is it even a published paper) and discuss some of the glaring flaws in it.

In the first section (I.) Mr. Phillips (who is not a doctor nor a research scientist by the way) claims that "on average, about 90 percent of infectious disease decline preceded vaccines" but he offers no evidence to support his claims.  A 90% reduction is quite extreme so one would think he should at least be able to back this up with some hard numbers... but that isn't the anti-vaxer way.

The most comical part of this section is his reference to scurvy - which has nothing to do with vaccines but rather increased knowledge about nutrition.  Scuvy is not a infectious disease at all and is caused by a lack of vitamin C, and this is the type of "disease" that Phillips uses to try to suggest vaccines don't work.  Not only is that idiotic and off point, but it is intellectually dishonest. 

Note to Mr. Hubbs: We are going to be talking about intellectual dishonesty several times, so you should probably look it up now so you understand the concept.

Phillips also mentions scarlet fever and typhoid fever as well as tuberculosis as diseases which have declined even without the useage of vaccines, but he conveniently fails to mention the reason they have declined is because they are easily treated with antibiotics.  Scarlet fever was in fact a significant issue until the point penicillin was discovered.  Typhoid fever is treated with antibiotics as well, although in the late 1800s a vaccine was in fact used commonly and with widespread success until sanitation methods caught up.  Only after increased sanitation became the norm did this disease get to the point a vaccine was no longer required, however that doesn't mean the disease has been eradicated because as recently as 2004 and 2005 there was a major outbreak in The Democratic Republic of Congo resulting in over 42,000 cases and over 200 deaths.

Tuberculosis (TB) is yet another example of where Mr. Phillips is being intellectually dishonest.  In fact there has been a vaccine for children for TB which has prevented it from being spread from person to person.  It stands to reason that if you can prevent a disease from being contracted in the first place, you can prevent it from being spread, so this is a case where a vaccine has greatly reduced the number of people who have ever been infected. 

Mr. Phillips attempts to claim there is no such vaccine at all, but that quite simply isn't the case, and TB vaccinations are routinely used in countries where TB is common.  Granted there is not an effective vaccine for adults, but there is one for children.  It is also worthy to note that there are actually more cases of TB on our planet now that at any point in history, so it is dishonest to suggest the disease has faded away into oblivion.  In fact, over two million deaths are attributed to TB each year, and there is growing concern that a newer more advanced vaccine is needed for both children as well as adults.

I'd suggest Mr. Phillips, as well as Mr. Hubbs, consult the following paper for additional factual information: http://www.ncbi.nlm.nih.gov/pubmed/16710326

Phillips then goes on to repeat what Mr. Hubbs has claimed in the past - that polio increased after the polio vaccine was introduced, but does Phillips offer any proof for this claim?  No, in fact the only "reference" he can source is the statement made by one Doctor in the 1960s and even that doctor didn't have any facts to support the viewpoint.  So let's look at the real numbers (just as we have done before).  Polio was first recognized in 1840 and major outbreaks occurred in Europe in the 1880s and soon thereafter in the US where it peaked in the 1950s and 60s. In 1952 there were at least 58,000 cases of polio diagnosed in the US.  By 1957 after a mass immunization campaign, there were only around 5,600 cases of polio diagnosed in the US, so I'm not exactly sure how Phillips (or Hubbs) thinks that is actually an increase in the cases of polio.  That is over a 90% reduction in less than five years that Mr. Phillips conveniently ignores, but the facts are by 1964 there were less than 125 diagnosed cases of polio in the entire nation, so not only did polio NOT increase after the vaccination was released, but it was practically eradicated.  To this day polio vaccines are still given on a regular basis, yet when is the last time you met someone in the modern era who was diagnosed with polio?  Exactly my point.

Since I'm a big fan of real sources, here is some more reading material for Phillips and Hubbs (although at this point I'm not sure either of them can actually understand complex subjects or interpret scientific data):
http://www.ncbi.nlm.nih.gov/pubmed/16741562
http://www.ncbi.nlm.nih.gov/pubmed/16899145
http://www.ncbi.nlm.nih.gov/pubmed/16153180
http://www.cdc.gov/vaccines/pubs/pinkbook/downloads/polio.pdf

Wow - all those glaring errors and that was just within part I of IX of Phillips hack-job article (that is part 1 of 9 for you Mr. Hubbs since I'm fairly certain you probably won't understand the concept of Roman Numerals).  I'm not sure I have the time to analyze every sentence here in great detail, but I think you get the point. 

In part II Phillips tries to suggest the risk-benefit assessment of vaccines isn't feasible, but it takes about 15 seconds to prove that wrong via numerous studies in pubmed.

Case in point:
http://www.ncbi.nlm.nih.gov/pubmed/21115586
http://www.ncbi.nlm.nih.gov/pubmed/20868284
http://www.ncbi.nlm.nih.gov/pubmed/20728932
http://www.ncbi.nlm.nih.gov/pubmed/20692031
http://www.ncbi.nlm.nih.gov/pubmed/20692030
http://www.ncbi.nlm.nih.gov/pubmed/20409210
http://www.ncbi.nlm.nih.gov/pubmed/20211953

Obviously there are hundreds more studies which prove vaccines are safe and effective - in fact my very first search using terms such as efficacy, vaccine, and placebo control trial brought up over 560 different studies to choose from.  Therefore to suggest we don't have the data to prove the effectiveness of vaccines or that we don't know enough to determine if the risk outweighs the benefit is simply (once again) intellectually dishonest.  So how many studies do we have which show that vaccines cause more harm to humans than the benefits they offer or how many studies do we have that show vaccines cause autism?  Zero.  The science speaks for itself, which is probably why Phillips likes to avoid speaking about it.

I'm actually starting to wonder if the antivaxers out there know how to actually do any research whatsoever or if they understand the scientific method, because it seems that they have the process backwards.  A typical antivaxer actually decides what outcome they wish to reach (that vaccines are bad) and then they backtrack into that position by cherry-picking data, referencing blogs and websites and articles while ignoring real science and facts.  Unfortunately that isn't how things work in the real world, and science will always prevail over opinion and quackery. 

This is why we have a scientific process which begins with defining a question, gathering information, forming a hypothesis (after the information is gathered... not before), performing experiments, analyzing the data from those experiements, interpreting the data from those experiments, drawing conclusions, publishing the results of the experiments, and then retesting to ensure the results can be replicated (which is often done by others to ensure the results are able to be replicated). You don't get to decide what the findings should be and then try to find ways to ensure the findings are valid, and you surely don't get to run around making claims that haven't undergone the rigors of the scientific process.

In part III, Phillips claims that "the belief that unvaccinated persons pose a risk of harm to others is without merit".  He goes on to say that "if vaccines work, then of course unvaccinated persons pose no risk to vaccinated persons at all" which just goes to show you that Phillips, and once again Mr. Hubbs, don't understand the concept of herd immunity whatsoever.  The reality is not everyone can get vaccines due to the reasons we have discussed in the past, so we can never have a population which is 100% vaccinated even if everyone was willing to voluntarily receive such vaccinations.  Those people who are unable to receive such vaccines are the very people at the highest risk, and those are the people we as responsible humans need to protect.

Phillips takes the typical antivaxer stance and tries to point out cases where there were outbreaks of diseases in "vaccinated populations", but again he misunderstands the data he tries to reference.  First, most if not all of these outbreaks can be traced back to unvaccinated people within the greater population who in turn spread the disease to others, and the vast majority of those infected are unvaccinated persons - that isn't even in dispute.  In many cases the disease can be traced back to someone who traveled to an area with lower rates of vaccination, contracted the disease, and then returned to the area they originated from where they will then spread the disease around.  Yes in some cases a small number of those who have received vaccines will become infected, but that is due to mutations in the disease and various strains.  When such mutations are realized, scientists will work on newer and improved vaccines to combat them in the future, but when you boil it down we probably wouldn't have these mutations and various strains if those people healthy enough to receive vaccines would in fact do so, thus preventing the disease in the first place.

Mr. Phillips also inaccurately tries to tie the number of swine flu vaccinated people in an area to the number of swine flu deaths, but this is a classic case of intellectual dishonesty in that he purposefully is attempting to manipulate the data to his liking.  Yes it is true that the US vaccinated more than other nations, but that doesn't automatically suggest such vaccinations actually creates swine flu or puts people at risk.  Instead, the reality is the US vaccinated more because we had the highest rates of infection before the vaccines were even available.  This is a classic case of cause and effect, although in Phillips' case he seems to believe effect comes before cause.  It is unfortunate he has such as misunderstanding of science, and even more unfortunate that the ignorant souls who will read his article without the ability to question the information due to their lack of understanding of complex subject matter and sub-par cognigtive abilities.

What bothers me most about Phillips however is that he makes very bold statements which he not only doesn't have sources to support, but that he couldn't support even if he wished.  Case in point, he claims the data he writes about "strongly suggest that the swine flu immunization campaigns may actually have been counterproductive" but he has no studies or peer-reviewed science to support that statement and it is entirely based upon a misunderstanding of  how vaccines are a response to disease rather than disease being a response to vaccines.  The studies I cited above will clearly show the effectiveness of vaccines in double-blind clinical trials, but Phillips conveniently (dishonestly?) ignores them.

I'm not going to bother to do the objective analysis any further because it is more than obvious that Mr. Hubbs is incapable of doing so himself, and I don't feel like being a teacher (nor do I wish to take the time to write a 15 page paper outlining all of the flaws in Phillips' original 6 page article).  However you can clearly see that even with a few minutes of time and an open mind, you can find countless flaws in Phillips' line of thinking and numerous faults in his conclusions.

The other issue at work here is the simply misunderstanding from Mr. Hubbs of the terms "proof" and the phrase "fully referenced".  First of all, Phillips provides no such proof for his claims, nor is he able to provide any science which proves his basic premise that vaccines offer more risk than benefit.  Second, this is nothing more than an opinion piece and not a research study nor does it even attempt to act as one, so the idea of "fully referenced" is downright silly.

Mr. Hubbs obviously doesn't understand that having footnotes on an article doesn't mean it is "fully referenced" because as I have shown above Phillips isn't able to provide sources for his most bold of statements (and when I say the most bold, I'm referring to some of the statements that Phillips himself has chosen to emphasize with underlining and/or Capital letters).  Not only is this a totally unscientific and poorly drafted editorial (I'm not even sure this piece does the term 'article' justice), but unfortunately for Mr. Hubbs and the other antivaxers out there, it is not fully sourced whatsoever.

Take a gander at some of the footnotes on the article and you will soon see what I mean.  Phillips references fellow antivaxer websites and blogs as his "sources" on more than one occasion.  He also lists several footnotes without supporting data or any reference to a publication where the data could be verified, and he even goes to far as to reference whale.to not once, but twice!  If this is the idea of a "fully referenced" article, then clearly Mr. Hubbs is more ignorant, and more disengaged from reality than I had previously thought.

Ok - so the editorial / article / hack piece or whatever you wish to call it is clearly horribly written, totally unsupported, and full of factual errors and shoddy understanding of the issues.  It is obviously produced knowing full well it relies upon intellectual dishonesty and manipulation of data and source material, and it hasn't given us a single piece of provable information which suggests vaccines are harmful or that the benefits don't outweigh the risks by a large margin.  So that much is settled, but who exactly is the man who wrote it, and why would Mr. Hubbs reference him?

As is the case with most antivaxers, Phillips isn't a research scientist or a doctor.  He isn't even a chiropractor and has never spent any time in a lab or participated in any research studies published in medical journals.  Truth be told, Phillips is actually a lawyer, and the more you read about him, the more unsettling it becomes that he is trying to act as an expert of some type of the issues of vaccinations.  It is so comical in fact, that I've had to devote an entire post to it because the more I read, the more humorous it became and I just couldn't fit it all here (as this post is already longer than it should be).  Thus I'll be releasing another post in upcoming days that will provide full detail about Alan Phillips and his professional credentials - or lack thereof.

The primary point here is obvious: Mr. Hubbs still does not understand science nor does he have the brain power to interpret data that is put before his very eyes.  Sad but true.

Monday, February 14, 2011

You can’t hide in the herd

Science-Based Medicine: You can’t hide in the herd

This is a really good article written by Dr. Joseph Albeitz which melds nicely with our last post on the concept of herd immunity.  Embedded within the article are links to two studies which show "that the act of refusing to vaccinate against pertussis (whooping cough) placed children at a 23 times greater risk of contracting pertussis."

The studies themselves can be found at links below.  Oh look - this first one is an actual published study with full sources and even a statement which says the seven authors (actual doctors mind you) have no financial relationships relevant to the article to disclose... thus no bias.  Also note that this study included hundreds upon hundreds of patients to ensure a broad range was included as opposed to something Wakefield might try to put together with a total of 12 patients (hand-picked and often fraudulently selected).

Parental Refusal of Pertussis Vaccination Is Associated With an Increased Risk of Pertussis Infection in Children

But wait... there's more.  Here is another published study which includes a full decade of data and hundreds of patients included.  If we were to take one sentence to sum this one up it would be the following: "Children of parents who refused varicella immunizations were at a greatly increased risk of varicella infection requiring medical care". 

Parental refusal of varicella vaccination and the associated risk of varicella infection in children.

Darn that science... it just keeps coming up with more facts that interfere and conflict with the antivaxer viewpoint.  We have real science and real studies proving the effectiveness of vaccines (and the proven risks to those who choose not to vaccinate), but vaccine deniers like Mr. Lowell Hubbs refuse to accept it.  Instead, they would rather confuse people by linking them over to some unpublished and non peer-reviewed opinion piece from a personal blog or send them over to the conspiracy theorist website whale.to. 

As always, facts and science cannot be disputed nor debated.

Saturday, February 12, 2011

Herd Immunity: A Scientific Fact

Many anti-vaxers (Mr. Hubbs included) seem to have a problem with the concept of herd immunity as if it is a myth, so I thought it was worthy of discussion to get the facts out there.  First of all the idea of herd immunity is that if enough people area vaccinated from a particular disease and therefore cannot contract that disease and/or pass it to others, then those who are not vaccinated will be protected.  Under most cases the threshold for such immunity equates to approximately 85% of the population being vaccinated for any given disease.

Unfortunately if the group that is not vaccinated grows too large, the 'herd' or population can no longer prevent diseases from being transmitted from person to person and this herd immunity loses its effectiveness.  The real issue here is that we always know there are a number of people who can't get vaccinated for one reason or another.  Maybe they are on chemotherapy or maybe they are on immune suppressive therapy for a chronic disease or maybe they have severe allergies that prevent them from receiving a specific vaccine (some vaccines use egg proteins for example).  These people have no choice but to skip a vaccination due to their other existing conditions, and they rely upon the rest of us to protect them. 

Dr. Paul Offit (probably one of the most well know and respected experts in the field of immunology and vaccinations) recently stated there are 500,000 people (I'm assuming he means people in the US) who fall into this category.  That means it is up to the other 300 million of us to get vaccinations in order to protect those who can't protect themselves.  Granted getting a vaccination is not a totally selfless act as it protects the person who gets the vaccination as well, but knowing it can prevent spreading disease to others is surely an added benefit.

Generally this system works fine, but in recent years due to fear mongering by pseudo-celebrities like Jenny McCarthy and due to fabricated studies like the one pushed forth by the now discredited Andrew Wakefield, there has been a growing number of people who are skipping their vaccines simply because they are too ignorant of the real science and too scared to take a chance.  To some degree these people are simply being selfish because they think the rest of us will protect them, but on the other hand these people are being dangerous because their lack of vaccinations means they can (and often do) contract diseases which are spread onto others.

Case in point, California is now under the worst pertussis outbreak in the last 50 years which has resulted in over 1,500 people contracting Whooping Cough and at least 10 deaths thus far.  The root cause of this outbreak?  People who skipped their vaccinations and thus spread the disease to others.  The primary reason for a growing number of people refusing to vaccinate their children or receive vaccinations themselves has been the discussion about a possible link to autism and all of the media attention which has surrounded the issue.  However, if you actually drill down on the issue you will find numerous peer-reviewed studies which have been performed that show no link between vaccines and autism, yet not a single peer-reviewed study anywhere which proves such a link exists.

This is generally the point where Mr. Hubbs would profess that the Wakefield "study" (not really a study, but more of a paper) proved such a link, but truth be told even when the Wakefield paper was published, it still was not able to prove such a link exists and never even claimed to.  Besides the fact that Wakefield didn't make the specific claim that the MMR vaccines causes autism (he merely eluded to a potential risk) and aside from the fact that Wakefield relied upon no more than a dozen hand picked children as his sample as opposed to hundreds of cases a real scientific study would have used, as it turns out his paper was based upon blatant fraud including the manipulation of patient data and cross-contamination of samples.

We should thank Mr. Wakefield however as he is credited with driving the vaccination rates in the UK down from 93% to around 75% and as a result the measles were actually declared to be an epidemic again in the UK.  This in turned resulted in countless people contracting the measles and in some cases it actually resulted in death, so be sure and mail a thank-you card to Wakefield for his great job (sarcasm intended).

Have I mentioned that not a single scientist has been able to replicate Wakefield's original findings?  Yea... that seems rather important when you try to suggest something is peer reviewed (the Wakefield study was not), but it does explain why so many of the original authors involved with Wakefield's paper later pulled their names from it.  Funny how not a single one of the "doctors" associated with the anti-vaxer movement has been able to replicate Wakefield's original findings even though they continue to profess his original work was sound - but that seems to be status quo for the antivax movement... make accusations but don't bother to back them up with evidence or any real science.

So with all of this said, we can clearly see the results when people decide to stop vaccinating.  Diseases spread, people suffer, and in some severe cases - people actually die.  So what has happened to the rates of autism during this same period of fear-mongering and vaccination avoidance?  If the anti-vaxers are correct the rates should be dropping due to fewer people being vaccinated, but sadly (and predictably) that hasn't been the case. 

Herd immunity is clearly not a myth and it works when people take responsibility for their health and the health of their families. Unfortunately, due to the desire to prey upon the fear of parents, the media has allowed this fraud to be perpetuated among the entire population which has resulted in many parents skipping the necessary vaccinations.  The good news is science is once again prevailing as more and more parents realize these fears are unfounded and the risks of not vaccinating are far too great to ignore. 

The other good news is the media is finally catching up with science and starting to report on the real facts including how Wakefield has been proven time and time again to be a lying fraud and how throughout all of the research and study which has been directed towards vaccines, none of it has proven any type of a link to autism.  In addition to this, due to the number of outbreaks of diseases that were once under control such as pertussis and measles, intelligent and logical people are discovering that herd immunity is not a myth, but rather an undisputed fact.